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Test Code CRCRU Chromium/Creatinine Ratio, Random, Urine

Reporting Name

Chromium/Creat Ratio, Random, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detecting chromium exposure

Method Name

CRCRR: Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)

CRETR: Enzymatic Colorimetric Assay


Ordering Guidance


 



Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic vial or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. See Metals Analysis Specimen Collection and Transport for complete instructions.


Specimen Type

Urine

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

0-17 years: Not established

>17 years: <0.8 mcg/g Creatinine

Interpretation

Chromium is principally excreted in the urine. Results greater than the reference range indicate either recent exposure to chromium or specimen contamination during collection.

 

The National Institute for Occupational Safety and Health document on occupational exposure reviews the data supporting use of urine to assess chromium exposure. The biological exposure index (BEI) for total chromium in urine measured at the end of the shift at the end of the workweek is 25 mcg/L. The BEI for the increase in total chromium during a shift is 10 mcg/L. A test for this specific purpose (CRUO / Chromium Occupational Exposure, Random, Urine) is available.

Day(s) Performed

Monday

Report Available

2 to 8 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82495

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRCRU Chromium/Creat Ratio, Random, U 13464-3

 

Result ID Test Result Name Result LOINC Value
CRETR Creatinine, Random, U 2161-8
607759 Chromium/Creat Ratio, U 13464-3

Profile Information

Test ID Reporting Name Available Separately Always Performed
CRCRR Chromium/Creat Ratio, U No Yes
CRETR Creatinine, Random, U No Yes