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Test Code CRT24 Creatinine, 24 Hour, Urine

Reporting Name

Creatinine, 24 HR, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function

 

Normalizing urinary analytes to account for the variation in urinary concentration

Method Name

Only orderable as part of a profile. For more information see:

-NMH24 / N-Methylhistamine, 24 Hour, Urine

-RB24 / Retinol-Binding Protein, 24 Hour, Urine

-A124 / Alpha-1-Microglobulin, 24 Hour, Urine

 

Enzymatic Colorimetric Assay


Specimen Required


Only orderable as part of a profile. For more information see:

-NMH24 / N-Methylhistamine, 24 Hour, Urine

-RB24 / Retinol-Binding Protein, 24 Hour, Urine

-A124 / Alpha-1-Microglobulin, 24 Hour, Urine


Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 30 days
  Frozen  30 days
  Ambient  14 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Only orderable as part of a profile. For more information see:

-NMH24 / N-Methylhistamine, 24 Hour, Urine

-RB24 / Retinol-Binding Protein, 24 Hour, Urine

-A124 / Alpha-1-Microglobulin, 24 Hour, Urine

 

Normal values mg per 24 hours:

Males: 930-2955 mg/24 hours

Females: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are less than 18 years of age.

 

For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html

Interpretation

Decreased creatinine clearance indicates decreased glomerular filtration rate. This can be due to conditions such as progressive renal disease, or result from adverse effect on renal hemodynamics that are often reversible including certain drugs or from decreases in effective renal perfusion (eg, volume depletion or heart failure).

 

Increased creatinine clearance is often referred to as "hyperfiltration" and is most commonly seen during pregnancy or in patients with diabetes mellitus, before diabetic nephropathy has occurred. It also may occur with large dietary protein intake.

Day(s) Performed

Monday through Sunday

Report Available

1 day

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRT24 Creatinine, 24 HR, U 65634-8

 

Result ID Test Result Name Result LOINC Value
CR_A Creatinine, 24 HR, U 2162-6
TM27 Collection Duration (h) 13362-9
VL69 Urine Volume (mL) 3167-4
CR_24 Creatinine Concentration, 24 HR, U 20624-3

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

 

Ambient

Yes

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

Yes

Boric Acid

Yes

Diazolidinyl Urea

Yes

6M Hydrochloric Acid

Yes

6M Nitric Acid

Yes

Sodium Carbonate

Yes

Thymol

No

Toluene

No