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HelpTest Code CRUZI Trypanosoma cruzi (Chagas) Antibody Panel, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.7 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Diagnosis of chronic Trypanosoma cruzi infection (Chagas disease) using two different methods
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CHAGS | T. cruzi Total Ab, EIA, S | No | Yes |
| CHAGL | T. cruzi IgG, LFA, S | No | Yes |
| CHAGI | T. cruzi Interpretation | No | Yes |
Method Name
CHAGS: Enzyme-Linked Immunosorbent Assay (ELISA)
CHAGL: Lateral Flow Assay (LFA)
Reporting Name
T. cruzi (Chagas) Ab Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
Reference Values
Negative
Reference values apply to all ages.
Interpretation
|
CHAGS result |
CHAGL result |
Interpretive comment |
|
Positive |
Positive |
Antibodies to Trypanosoma cruzi (Chagas disease) detected by two separate methods, suggesting current or past infection. Results should be interpreted alongside clinical presentation and exposure history. |
|
Positive |
Negative |
Antibodies to Trypanosoma cruzi (Chagas disease) detected by one of two assays. Discordant results can be resolved through submission of a new sample for testing or through additional testing at a public health laboratory. |
|
Positive |
Invalid |
Submission of a new sample is recommended to resolve discordant results. |
|
Indeterminate |
Positive |
Antibodies to Trypanosoma cruzi (Chagas disease) detected by one of two assays. Discordant results can be resolved through submission of a new sample for testing or through additional testing at a public health laboratory. |
|
Indeterminate |
Negative |
Submission of a new sample is recommended to resolve discordant results. |
|
Indeterminate |
Invalid |
Submission of a new sample is recommended to resolve discordant results. |
|
Negative |
Positive |
Antibodies to Trypanosoma cruzi (Chagas disease) detected by one of two assays. Discordant results can be resolved through submission of a new sample for testing or through additional testing at a public health laboratory. |
|
Negative |
Negative |
No antibodies to Trypanosoma cruzi (Chagas disease) detected. False negative results may occur in patients tested within 4 weeks of infection. |
|
Negative |
Invalid |
Submission of a new sample is recommended to resolve discordant results. |
Day(s) Performed
Monday
Report Available
Same day/1 to 8 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86753 x2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CRUZI | T. cruzi (Chagas) Ab Panel, S | 23785-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CHAGS | T. cruzi Total Ab, EIA, S | 57320-4 |
| CHAGL | T. cruzi IgG, LFA, S | 87994-0 |
| CHAGI | T. cruzi Interpretation | 59464-8 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.