Test Code CRWB Chromium, Blood
Reporting Name
Chromium, BPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Monitoring exposure to chromium using whole blood specimens
Monitoring metallic prosthetic implant wear
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Ordering Guidance
High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Specimen Required
Container/Tube: Royal blue top (EDTA) Vacutainer plastic trace element blood collection tube
Specimen Volume: 1 mL
Collection Instructions:
1. See Metals Analysis Specimen Collection and Transport for complete instructions.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Type
Whole bloodSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Microtainer | Reject |
Reference Values
0-17 years: Not established
≥18 years: <1.0 ng/mL
Interpretation
Results greater than the reference range indicate exposure to chromium (see Cautions about specimen collection).
Prosthesis wear is known to result in increased circulating concentration of metal ions. Increased blood trace element concentrations in the absence of corroborating clinical information do not independently predict prosthesis wear or failure.
Day(s) Performed
Tuesday, Wednesday, Friday
Report Available
1 to 4 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82495
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CRWB | Chromium, B | 5619-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
65601 | Chromium, B | 5619-2 |