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HelpTest Code DASM4 Drugs of Abuse Screen, Meconium 4
Reporting Name
Drugs of Abuse Screen, Meconium 4Performing Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Identifying amphetamines (and methamphetamines), opiates, as well as metabolites of cocaine and marijuana in meconium specimens
Method Name
Competitive Chemiluminescent Immunoassay (CIA)
Ordering Guidance
For chain-of-custody testing, order DSM4X / Drugs of Abuse Screen 4, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Type
MeconiumSpecimen Minimum Volume
0.45 g (approximately 0.5 teaspoon)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Meconium | Frozen (preferred) | 21 days | |
| Refrigerated | 21 days | ||
| Ambient | 72 hours |
Reject Due To
| Grossly bloody | Reject, Pink OK |
| Stool Diapers |
Reject |
Reference Values
Negative
Positives are reported with a quantitative liquid chromatography tandem mass spectrometry result.
Cutoff concentrations by competitive chemiluminescent immunoassay:
Amphetamines: 100 ng/g
Methamphetamine: 100 ng/g
Benzoylecgonine (cocaine metabolite): 100 ng/g
Opiates: 100 ng/g
Tetrahydrocannabinol carboxylic acid (marijuana metabolite): 20 ng/g
Interpretation
A positive result indicates that the baby was exposed to the drugs indicated.
Day(s) Performed
Monday through Saturday
Report Available
1 to 2 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80307
80324 (if appropriate)
80359 (if appropriate)
80353 (if appropriate)
80361 (if appropriate)
80365 (if appropriate)
80349 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DASM4 | Drugs of Abuse Screen, Meconium 4 | 49046-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 32078 | Amphetamine | 26895-3 |
| 32080 | Methamphetamine | 27289-8 |
| 32082 | Cocaine | 26956-3 |
| 32084 | Opiate | 29158-3 |
| 32086 | Tetrahydrocannabinol | 26893-8 |
| 32087 | Chain of Custody | 77202-0 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| AMPHM | Amphetamines, Confirmation, M | Yes | No |
| COKEM | Cocaine and Metabolites, Confirm, M | Yes | No |
| OPATM | Opiate Confirmation, M | Yes | No |
| THCM | Carboxy-THC Confirmation, M | Yes | No |
Testing Algorithm
Testing begins with immunoassay screen. Positive results are confirmed and quantified by liquid chromatography tandem mass spectrometry at an additional charge.