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Test Code EHRC Ehrlichia chaffeensis (HME) Antibody, IgG, Serum

Reporting Name

Ehrlichia Chaffeensis (HME) Ab, IgG

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

An adjunct in the diagnosis of ehrlichiosis

 

Seroepidemiological surveys of the prevalence of the infection in certain populations

Method Name

Immunofluorescence Assay (IFA)


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Reference Values

<1:64

Reference values apply to all ages.

Interpretation

A positive immunofluorescence assay result (titer ≥1:64) suggests current or previous infection. In general, the higher the titer, the more likely the patient has an active infection. Four-fold rises in titer also indicate active infection.

 

Previous episodes of ehrlichiosis may produce a positive serology result although antibody levels decline significantly during the year following infection.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86666

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EHRC Ehrlichia Chaffeensis (HME) Ab, IgG 47405-6

 

Result ID Test Result Name Result LOINC Value
81478 Ehrlichia Chaffeensis (HME) Ab, IgG 47405-6

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.

Testing Algorithm

For more information see Acute Tick-Borne Disease Testing Algorithm