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Test Code EMAT Endomysial Antibodies, IgA, Titer, Serum

Reporting Name

EMA Titer, S (IgA)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Confirmation of a positive IgA-endomysial antibodies result

Method Name

Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.

 

Indirect Immunofluorescence Assay (IFA)


Specimen Required


Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Only orderable as a reflex. For more information see EMA / Endomysial Antibodies, IgA, Serum.

 

Negative

Interpretation

The finding of IgA-endomysial antibodies (EMA) is highly specific for dermatitis herpetiformis or celiac disease.

 

The titer of IgA-EMA generally correlates with the severity of gluten-sensitive enteropathy.

 

If patients strictly adhere to a gluten-free diet, the titer of IgA-EMA should begin to decrease within 6 to 12 months of onset of dietary therapy.

 

Occasionally, the staining results cannot be reliably interpreted as positive or negative because of strong smooth muscle staining, weak EMA staining, or other factors. In these cases, the results will be reported as "indeterminate," and additional testing is recommended; see TTGA / Tissue Transglutaminase Antibody, IgA, Serum and IGA / Immunoglobulin A (IgA), Serum.

Day(s) Performed

Monday through Friday

Report Available

2 days

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86231

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EMAT EMA Titer, S (IgA) 27038-9

 

Result ID Test Result Name Result LOINC Value
65091 EMA Titer, S (IgA) 27038-9