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Test Code EURO Phospholipase A2 Receptor, Enzyme Linked Immunosorbent Assay, Serum

Reporting Name

Phospholipase A2 Receptor, ELISA, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Distinguishing primary from secondary membranous nephropathy

Method Name

Only orderable as part of a profile. For more information see PMND1 / Primary Membranous Nephropathy Diagnostic Cascade, Serum

 

Enzyme-Linked Immunosorbent Assay (ELISA)


Specimen Required


Only orderable as part of a profile. For more information see PMND1 / Primary Membranous Nephropathy Diagnostic Cascade, Serum.

 

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial within 2 hours of collection


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  8 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Only orderable as part of a profile. For more information see PMND1 / Primary Membranous Nephropathy Diagnostic Cascade, Serum.

 

<14 RU/mL: Negative

14 to 19 RU/mL: Borderline

≥20 RU/mL: Positive

Interpretation

Therapy outcome can be monitored by measuring the anti-phospholipase A2 receptor antibody titer. A titer increase, decrease, or disappearance generally precedes a change in clinical status. Thus, the determination of the antibody titer has a high predictive value with respect to clinical remission, relapse, or risk assessment after kidney transplantation.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

3 to 7 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
EURO Phospholipase A2 Receptor, ELISA, S 73737-9

 

Result ID Test Result Name Result LOINC Value
EURO Phospholipase A2 Receptor, ELISA, S 73737-9