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HelpTest Code FENTX Fentanyl with Metabolite Confirmation, Chain of Custody, Random, Urine
Reporting Name
Fentanyl w/metabolite Conf, CoC, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Detection and confirmation of illicit drug use involving fentanyl
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was under the control of personnel involved with testing the specimen at all times; this control implies that the opportunity for specimen tampering would be limited.
Method Name
Immunoassay/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Ordering Guidance
Specimen Required
Container/Tube: Chain of Custody Kit (T282) containing the specimen containers, seals, and documentation required.
Specimen Volume: 5 mL
Collection Instructions: Collect random urine specimen in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Additional Information: Submitting less than 5 mL will compromise the ability to perform all necessary testing.
Specimen Type
UrineSpecimen Minimum Volume
2.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 21 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | Reject |
Reference Values
Negative
Cutoff concentrations:
Immunoassay screen
<2 ng/mL
Fentanyl by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
0.2 ng/mL
Norfentanyl by LC-MS/MS
1.0 ng/mL
Interpretation
The presence of fentanyl above 0.20 ng/mL or norfentanyl above 1.0 ng/mL is a strong indicator that the patient has used fentanyl.
Day(s) Performed
Monday through Friday
Report Available
4 to 7 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80354
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FENTX | Fentanyl w/metabolite Conf, CoC, U | 67822-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 36653 | Fentanyl Immunoassay Screen | 59673-4 |
| 36191 | Fentanyl by LC-MS/MS | 58381-5 |
| 36190 | Norfentanyl by LC-MS/MS | 58383-1 |
| 36192 | Fentanyl Interpretation | 69050-3 |
| 36193 | Chain of Custody | 77202-0 |
Forms
1. Chain of Custody Request is included in the Chain-of-Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
| ADLTX | Adulterants Survey, CoC, U | Yes | Yes |
Testing Algorithm
Adulterants testing will be performed on all chain of custody urine samples as per regulatory requirements.