Test Code FERR1 Ferritin, Serum
Specimen Required
Patient Preparation: Â For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Useful For
Aiding in the diagnosis of iron deficiency and iron overload conditions
Differentiating iron deficiency anemia and anemia of chronic disease
Special Instructions
Method Name
Electrochemiluminescence Immunoassay
Reporting Name
Ferritin, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 7 days | |
Frozen | 365 days | ||
Ambient | 24 hours |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | Reject |
Reference Values
Males:
0 days-4 weeks: 150-973 mcg/L
5 weeks-5 months: 9-580 mcg/L
6 months-9 years: 6-111 mcg/L
10-17 years: 15-201 mcg/L
≥18 years: 31-409 mcg/L
Females:
0 days-4 weeks: 150-973 mcg/L
5 weeks-5 months: 9-580 mcg/L
6 months-17 years: 8-115 mcg/L
18-50 years: 6-175 mcg/L
≥51 years: 11-328 mcg/L
Interpretation
Hypoferritinemia is associated with increased risk for developing iron deficiency where iron deficiency is sufficient to reduce erythropoiesis causing hemoglobin concentrations to fall. Latent iron deficiency occurs when serum ferritin is low without low hemoglobin.
Hyperferritinemia is associated with iron overload conditions including hereditary hemochromatosis where concentrations may exceed 1000 mcg/L. Non-iron overload hyperferritinemia may be caused by common liver disorders, neoplasms, acute or chronic inflammation, and hereditary hyperferritinemia-cataract syndrome.
For more information about hereditary hemochromatosis testing, see Hereditary Hemochromatosis Algorithm.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in RochesterTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82728
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
FERR1 | Ferritin, S | 20567-4 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
FERR1 | Ferritin, S | 20567-4 |
Testing Algorithm
For more information see Hereditary Hemochromatosis Algorithm.