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Test Code GENRA Gentamicin, Random, Serum

Reporting Name

Gentamicin, Random, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Monitoring adequacy of serum concentration during gentamicin therapy in specimens for which no collection timing information is provided

Method Name

Turbidimetric Immunoassay


Specimen Required


Collection Container/Tube: 

Preferred: Serum gel 

Acceptable: Red top 

Submission Container/Tube: Plastic vial 

Specimen Volume: 0.5 mL 

Collection Instructions:  

1. Serum gel tubes should be centrifuged within 2 hours of collection. 

2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.


Specimen Type

Serum

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject

Reference Values

Gentamicin, Peak

Therapeutic: 3.0-12.0 mcg/mL

Toxic: >12.0 mcg/mL

Gentamicin, Trough

Therapeutic: <2.0 mcg/mL

Toxic: >2.0 mcg/mL

Interpretation

Goal peak concentrations levels depend on the type of infection being treated. Goal trough levels should be less than 2.0 mcg/mL. Peak targets are generally between 3.0 and 12.0 mcg/mL for conventional dosing. Prolonged exposure to either peak levels exceeding 12.0 mcg/mL or to trough levels exceeding 2.0 mcg/mL may lead to toxicity.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

80170

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GENRA Gentamicin, Random, S 35668-3

 

Result ID Test Result Name Result LOINC Value
GENRA Gentamicin, Random, S 35668-3

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.