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Test Code GLYCC Glycine Receptor Alpha1 IgG, Cell Binding Assay, Spinal Fluid

Reporting Name

Glycine Alpha1 LCBA, CSF

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk, or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using spinal fluids specimens

Method Name

Live Cell-Binding Assay (LCBA)


Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 2 mL


Specimen Type

CSF

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Negative

Interpretation

In the appropriate clinical context, this profile is consistent with a stiff-person syndrome spectrum disorder (classical stiff-person, stiff-limb, or progressive encephalomyelitis with rigidity and myoclonus [PERM]). A paraneoplastic cause should be considered.

Day(s) Performed

Thursday

Report Available

5 to 10 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

0431U

LOINC Code Information

Test ID Test Order Name Order LOINC Value
GLYCC Glycine Alpha1 LCBA, CSF 96497-3

 

Result ID Test Result Name Result LOINC Value
606973 Glycine Alpha1 LCBA, CSF 96497-3

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.