Test Code HMHA Heavy Metals, Hair
Reporting Name
Heavy Metals, HairPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Detection of nonacute arsenic, mercury, and lead exposure using hair specimens
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Necessary Information
Indicate source of hair (axillary, head, or pubic), if known
Specimen Required
Supplies: Hair and Nails Collection Kit (T565)
Specimen Volume: 0.2 g
Collection Instructions: Prepare and transport specimen per the instructions in kit or see Collecting Hair and Nails for Metals Testing.
Specimen Type
HairSpecimen Minimum Volume
0.05 g
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Hair | Ambient (preferred) | ||
Frozen | |||
Refrigerated |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
ARSENIC
0-15 years: Not established
≥16 years: <1.0 mcg/g of hair
LEAD
<4.0 mcg/g of hair
Reference values apply to all ages.
MERCURY
0-15 years: Not established
≥16 years:<1.0 mcg/g of hair
Interpretation
Hair grows at a rate of approximately 0.5 inch/month. Hair keratin synthesized today will protrude through the skin in approximately 1 week. Thus, a hair specimen collected at the skin level represents exposure of 1 week ago, 1 inch distally from the skin represents exposure 2 months ago, etc.
ARSENIC
Hair arsenic levels above 1.00 mcg/g dry weight may indicate excessive exposure. It is normal for some arsenic to be present in hair, as everybody is exposed to trace amounts of arsenic from the normal diet.
The highest hair arsenic observed at Mayo Clinic was 210 mcg/g dry weight in a case of chronic exposure, which was the cause of death.
MERCURY
Normally, hair contains less than 1 mcg/g of mercury; any amount more than this indicates that exposure to more than normal amounts of mercury may have occurred.
LEAD
Normal hair lead content is below 4.0 mcg/g. While hair lead content above 10.0 mcg/g may indicate significant lead exposure, hair is also subject to potential external contamination with environmental lead and contaminants in artificial hair treatments (eg, dyeing, bleaching, or permanents). Ultimately, the hair lead content needs to be interpreted in addition to the overall clinical scenario including symptoms, physical findings, and other diagnostic results when determining further actions.
Day(s) Performed
Tuesday
Report Available
2 to 8 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82175-ASHA
83655-PBHA
83825-HGHAR
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HMHA | Heavy Metals, Hair | 34667-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
31896 | Arsenic, Hair | 5584-8 |
31900 | Mercury, Hair | 5686-1 |
31898 | Lead, Hair | 5673-9 |
PBHSC | Specimen Source | 31208-2 |
HGHSC | Specimen Source | 31208-2 |
ASHSC | Specimen Source | 31208-2 |
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ASHA | Arsenic, Hair | Yes | Yes |
PBHA | Lead, Hair | Yes | Yes |
HGHAR | Mercury, Hair | Yes | Yes |