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Test Code HSTNI Troponin I, High Sensitivity, Plasma

Reporting Name

Troponin I, High Sensitivity, P

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Excluding the diagnosis of acute coronary syndromes

 

Explaining troponin T elevations related to skeletal myopathy and/or assay interferences

Method Name

Electrochemiluminescence Immunoassay


Specimen Required


Collection Container/Tube:

Preferred: Mint green top (lithium heparin gel)

Acceptable: Green top (lithium heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Plasma gel tube should be centrifuged within 2 hours of collection.

2. Green-top tube should be centrifuged, and the plasma aliquoted into a plastic vial within 2 hours of collection.


Specimen Type

Plasma

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Frozen (preferred) 180 days
  Refrigerated  48 hours
  Ambient  4 hours

Reject Due To

Gross hemolysis Reject

Reference Values

Males ≥18 years: ≤20 ng/L

Females ≥18 years: ≤15 ng/L

 

Reference values have not been established for patients younger than 18 years old.

Interpretation

Elevations in cardiac troponin T (cTnT) can be due to skeletal muscle disease and not cardiac disease in certain circumstances. One way to unmask such elevations is to measure cardiac troponin I (cTnI), which will be normal in that situation. In addition, at times there are interferences that can cause spurious increases or decreases in cTnT values. Conceptually, these same interferences can occur with cTnI but in any given case, the likelihood of having both assays be confounded in that way is highly unusual. Thus, potential false-positive results would be unmasked by a normal cTnI and false-negative results by an elevated value.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

2 to 3 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84484

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HSTNI Troponin I, High Sensitivity, P 89579-7

 

Result ID Test Result Name Result LOINC Value
HSTNI Troponin I, High Sensitivity, P 89579-7

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.