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HelpTest Code KRASD Cell-Free DNA KRAS 12, 13, 61,146, Blood
Reporting Name
cfDNA KRAS 12, 13, 61, 146 BloodPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
An alternative to invasive tissue biopsies for the determination of KRAS 12, 13, 61,146 (G12A, G12C, G12D, G12R, G12S, G12V, G13D, Q61K, Q61L, Q61R, Q61H, and A146T) mutation status
Detecting molecular markers associated with response or resistance to specific therapy
This test is not intended as a screening test to identify cancer.
Method Name
Digital Droplet Polymerase Chain Reaction (PCR)
Ordering Guidance
This test is not a prenatal screening test
Shipping Instructions
1. Samples should be transported at ambient temperature or refrigerated (4° C).
2. Samples are viable for 7 days in the Streck Black/Tan Top Tube Kit (T715).
Specimen Required
Supplies: Streck Black/Tan Top Tube Kit (T715)
Container/Tube: Streck Cell-Free DNA blood collection kit
Specimen Volume: Two 10-mL Streck Cell-Free DNA blood collection tubes
Additional Information: Only blood collected in Streck Cell-Free DNA BCT tubes will be accepted for analysis. Whole blood will be processed to produce platelet-poor plasma before cfDNA isolation.
Specimen Type
Whole bloodSpecimen Minimum Volume
One 10 mL Streck tube
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Ambient (preferred) | 7 days | Streck Black/Tan top |
| Refrigerated | 7 days | Streck Black/Tan top |
Reject Due To
| Specimen collected in tube other than Streck Cell-Free DNA collection tube | Reject |
Reference Values
An interpretive report will be provided
Interpretation
The interpretation of molecular biomarker analysis includes an overview of the results and the associated diagnostic, prognostic, and therapeutic implications.
Day(s) Performed
Varies
Report Available
5 to 10 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81275
81276
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| KRASD | cfDNA KRAS 12, 13, 61, 146 Blood | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 113123 | Result Summary | 50397-9 |
| 113508 | Result | 75974-6 |
| 113125 | Interpretation | 69047-9 |
| 113126 | Additional Information | 48767-8 |
| 113127 | Specimen | 31208-2 |
| 113128 | Source | 31208-2 |
| 113129 | Released By | 18771-6 |
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.