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HelpTest Code MMLSA Antimicrobial Susceptibility, Anaerobic Bacteria, Minimal Inhibitory Concentration, Varies
Infectious
Reporting Name
Susceptibility, Anaerobic, MICPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Determining the in vitro susceptibility on isolates of anaerobic bacteria involved in human infections
Directing antimicrobial therapy for anaerobic bacterial infections
Method Name
Minimal Inhibitory Concentration (MIC) by Agar Dilution
Shipping Instructions
For shipping information, see Infectious Specimen Shipping Guidelines.
Necessary Information
Organism identification and specimen source are required.
Specimen Required
Specimen Type: Organism in pure culture
Acceptable Sources: Isolates from blood cultures, bone and joint infections, or brain abscesses, and organisms isolated in pure culture from other sources
Supplies:
Anaerobic Transport Tube (T588)
Infectious Container, Large (T146)
Container/Tube:
Preferred: Anaerobic transport tube
Acceptable: Thioglycollate broth or any other suitable anaerobic transport system
Collection Instructions :
1. Organism must be in pure culture and actively growing. Do not submit mixed cultures.
2. Place specimen in a large infectious container and label as an etiologic agent/infectious substance if appropriate
Specimen Type
VariesSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Varies | Ambient | ||
Reject Due To
| Agar plate | Reject |
Reference Values
Susceptibility results are reported as minimal inhibitory concentration (MIC) in mcg/mL. Breakpoints (also known as clinical breakpoints) are used to categorize an organism as susceptible, susceptible-dose dependent, intermediate, resistant, or nonsusceptible according to breakpoint setting organizations, either the Clinical and Laboratory Standards Institute (CLSI) or the European Committee on Antimicrobial Susceptibility Testing (EUCAST), as applicable.
In some instances, an interpretive category cannot be provided based on available data; therefore, the following comment will be included on the report: There are no established interpretive guidelines for agents reported without interpretations.
For information regarding CLSI and EUCAST susceptibility interpretations, see Susceptibility Interpretative Category Definitions.
Interpretation
A "susceptible" category result and a low minimal inhibitory concentration value indicates in vitro susceptibility of the organism to the antimicrobial tested.
For interpretation of various antimicrobial susceptibility interpretive categories (ie, susceptible, intermediate, resistant, or epidemiological cutoff value), see Reference Values.
Day(s) Performed
Monday through Sunday
Report Available
8 to 14 daysTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
87186-Antimicrobial Susceptibility, Anaerobic Bacteria, MIC
87076-Organism Ref for ID, Anaerobic Bact (if appropriate)
87076-Anaerobe Ident (if appropriate)
87076-Id MALDI-TOF Mass Spec Anaerobe (if appropriate)
87153-Anaerobe ident by sequencing (if appropriate)
87150-Identification by PCR (if appropriate)
87185-Beta Lactamase (if appropriate)
87181-Anaerobe Susceptibility per Agent (if appropriate)
87150-mecA PCR (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MMLSA | Susceptibility, Anaerobic, MIC | 50545-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| MMLSA | Susceptibility, Anaerobic, MIC | 50545-3 |
Forms
If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ANAID | Anaerobe Ident | No, (Bill Only) | No |
| RMALA | Id MALDI-TOF Mass Spec Anaerobe | No, (Bill Only) | No |
| ISAN | Anaerobe Ident by Sequencing | No, (Bill Only) | No |
| PCRID | Identification by PCR | No, (Bill Only) | No |
| BLA | Beta Lactamase | No, (Bill Only) | No |
| SANA | Anaerobe Suscep per agent | No, (Bill Only) | No |
| ANIDE | Organism Ref for ID, Anaerobic Bact | Yes | No |
| MECAB | mecA PCR Test, Bill Only | No, (Bill Only) | No |
Testing Algorithm
When this test is ordered, the reflex tests may be performed at an additional charge. All anaerobic bacterial organisms recovered will automatically have susceptibility testing performed and billed as appropriate. Antimicrobial agents appropriate to the organism and specimen source will be tested according to Mayo Clinic's practice and the laboratory's standard operating procedures.
For a listing of the antimicrobials routinely tested in this laboratory as well as antimicrobials that may be tested upon request, see Anaerobic Bacteria Antimicrobials. If the organism or antimicrobial agent of interest is not listed in this table, call 800-533-1710 and ask to speak to the Bacteriology Anaerobe Laboratory.
If organism identification is not provided within 72 hours of specimen receipt, referred anaerobic bacteria identification will be performed at an additional charge.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| BATTA | Anaerobe Suscep Battery | No | Yes |