Test Code MNS Manganese, Serum
Reporting Name
Manganese, SPerforming Laboratory

Useful For
Monitoring manganese exposure using serum specimens
Nutritional monitoring
Method Name
Triple-Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours
Supplies:
-Metal Free B-D Tube (No Additive), 6 mL (T184)
-Metal Free Specimen Vial (T173)
Collection Container/Tube: 6 mLPlain, royal blue-top Vacutainer plastic trace element blood collection tube
Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial
Specimen Volume: 1.6 mL
Collection Instructions: See Metals Analysis Specimen Collection and Transport for complete instructions.
Specimen Type
SerumSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 28 days | METAL FREE |
Ambient | 28 days | METAL FREE | |
Frozen | 28 days | METAL FREE |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | OK |
Gross icterus | OK |
Reference Values
0-17 years: Not established
≥18 years: 0.4-0.9 ng/mL
Interpretation
Serum manganese results above the reference values suggest recent exposure. Serum concentrations in combination with brain magnetic resonance imaging scans and neurological assessment may be used to detect excessive exposure.
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83785
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
MNS | Manganese, S | 5683-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8413 | Manganese, S | 5683-8 |