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HelpTest Code NIU Nickel, 24 Hour, Urine
Reporting Name
Nickel, 24 Hr, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Preferred test for biomonitoring patients for nickel exposure to minimize any potential diurnal variation
Method Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
Ordering Guidance
This test is preferred for the determination of nickel exposure, but serum concentrations can be used to verify an elevated urine concentration. For more information see NIS / Nickel, Serum.
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Type
UrineSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
0-17 years: not established
≥18 years: <6.0 mcg/24h
Interpretation
Values of 6.0 mcg/24-hour specimen and higher represent possible environmental or occupational exposure.
Hypernickelemia, in the absence of exposure, may be an incidental finding or could be due to specimen contamination.
Day(s) Performed
Thursday
Report Available
2 to 8 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83885
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NIU | Nickel, 24 Hr, U | 5705-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8626 | Nickel, 24 Hr, U | 5705-9 |
| TM18 | Collection Duration | 13362-9 |
| VL30 | Urine Volume | 3167-4 |