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HelpTest Code NSYPH Syphilis IgG Enzyme Immunoassay, Serum
Specimen Required
Collection Container/Tube: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Useful For
An aid in the diagnosis of infection with Treponema pallidum
Routine prenatal screening
This test is not useful for diagnosis of congenital syphilis.
This test is not offered as a screening or confirmatory test for blood donor specimens.
Method Name
Enzyme Immunoassay (EIA)
Reporting Name
Syphilis IgG EIA, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat-inactivated specimen | Reject |
Reference Values
Nonreactive
Reference values apply to all ages
Interpretation
Nonreactive:
No serologic evidence of exposure to Treponema pallidum (syphilis). Repeat testing may be considered in patients with suspected acute or primary syphilis.
Equivocal:
Recommend follow-up testing in 10 to 14 days if clinically indicated.
Reactive:
Results suggest infection with T pallidum at some point in time. Results do not distinguish between recent or past infection, or between treated and untreated syphilis as treponema-specific IgG may remain elevated despite appropriate therapy. Falsely reactive treponemal results may occur; additional testing by a non-treponemal assay is recommended if not previously performed on this sample.
Day(s) Performed
Monday through Friday, Sunday
Report Available
Same day/1 to 3 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86780
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NSYPH | Syphilis IgG EIA, S | 47238-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| NSYPH | Syphilis IgG EIA, S | 47238-1 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.