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Test Code OROT Orotic Acid, Random, Urine

Reporting Name

Orotic Acid, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of the differential diagnosis of hyperammonemia and hereditary orotic aciduria

 

Sensitive indicator of ornithine transcarbamylase (OTC) activity after administration of allopurinol or a protein load to identify OTC carriers

Method Name

Colorimetric


Necessary Information


1. Patient's age is required.

2. Provide a reason for testing.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random or timed urine specimen.

2. No preservative needed.


Specimen Type

Urine

Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen 30 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

<2 weeks: 1.4-5.3 mmol/mol creatinine

2 weeks-1 year: 1.0-3.2 mmol/mol creatinine

2-10 years: 0.5-3.3 mmol/mol creatinine

≥11 years: 0.4-1.2 mmol/mol creatinine

Interpretation

The value for the orotic acid concentration is reported. The interpretation of the result must be correlated with clinical and other laboratory findings.

Day(s) Performed

Tuesday, Thursday

Report Available

4 to 8 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83921

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OROT Orotic Acid, U 17869-9

 

Result ID Test Result Name Result LOINC Value
8905 Orotic Acid, U 17869-9