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HelpTest Code ORTHP Orthostatic Proteinuria, Random, Urine
Specimen Required
Patient Preparation: Specimens should be collected before fluorescein is given or not collected until at least 24 hour later.
Container/Tube: Plastic, 5-mL tube
Specimen Volume: 4 mL
Collection Instructions:
1. This is a nighttime (supine) collection.
2. Void immediately prior to lying down to sleep.
3. Collect an 8-hour (nighttime) urine specimen.
4. Upon awaking in the morning, the patient should immediately void into the specimen cup.
4. No preservative.
5. Invert well before taking 4-mL (maximum) aliquot.
Useful For
Diagnosis of orthostatic proteinuria
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PRCON | Protein, Total, Random, U | No | Yes |
| RATO2 | Protein/Creatinine Ratio | No | Yes |
| CRETR | Creatinine, Random, U | No | Yes |
Method Name
PRCON: Turbidimetry
CRETR: Enzymatic Colorimetric Assay
RATO2: Calculation
Reporting Name
Orthostatic Proteinuria, Random, USpecimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 30 days | ||
| Ambient | 24 hours |
Reject Due To
| All specimens will be evaluated at Mayo Clinic Laboratories for test suitability. |
Reference Values
PROTEIN/CREATININE RATIO:
≥18 years: <0.18 mg/mg creatinine
CREATININE:≥18 years = 16-326 mg/dL
Reference values have not been established for patients younger than 18 years of age.
Interpretation
First-morning urine protein-to-creatinine ratio below 0.20 mg/mg creatinine supports the diagnosis of orthostatic proteinuria, while a result above 0.20 mg/mg creatinine does not support this diagnosis.
Further investigation into other etiologies for proteinuria may be warranted.
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 dayPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
CRETR- 82570
PRCON- 84156
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| ORTHP | Orthostatic Proteinuria, Random, U | 87434-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CRETR | Creatinine, Random, U | 2161-8 |
| PRCON | Protein, Total, Random, U | 2888-6 |
| RATO2 | Protein/Creatinine Ratio | 2890-2 |