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HelpTest Code OXYCX Oxycodone with Metabolite Confirmation, Chain of Custody, Random, Urine
Reporting Name
Oxycodone w/metabolite Conf, CoC, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Detection and quantification of oxycodone, oxymorphone, noroxycodone, and noroxymorphone in urine
Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by demonstrating that it was always under the control of personnel involved with testing the specimen; this control implies that the opportunity for specimen tampering would be limited.
Method Name
Immunoassay/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Specimen Required
Supplies: Chain of Custody Kit (T282)
Container/Tube: Chain of custody kit containing the specimen containers, seals, and documentation is required.
Specimen Volume: 5 mL
Collection Instructions: Collect urine specimen in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain of custody testing.
Specimen Type
UrineSpecimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Reference Values
Negative
Cutoff concentrations:
Oxycodone Immunoassay screen: 100 ng/mL
By liquid chromatography tandem mass spectroscopy:
Oxycodone: 25 ng/mL
Noroxycodone: 25 ng/mL
Oxymorphone: 25 ng/mL
Noroxymorphone: 25 ng/mL
Interpretation
This procedure reports the total urine concentration; this is the sum of the unconjugated and conjugated forms of the parent drug.
Day(s) Performed
Monday through Friday
Report Available
2 to 5 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80365
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| OXYCX | Oxycodone w/metabolite Conf, CoC, U | 94304-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 36300 | Oxycodone Immunoassay Screen | 19642-8 |
| 61728 | Oxycodone-by LC-MS/MS | 16249-5 |
| 42012 | Noroxycodone-by LC-MS/MS | 61425-5 |
| 35964 | Oxymorphone-by LC-MS/MS | 17395-5 |
| 42013 | Noroxymorphone-by LC-MS/MS | 90894-7 |
| 36023 | Oxycodone Interpretation | 69050-3 |
| 36028 | Chain of Custody | 77202-0 |
Forms
1. Chain of Custody Request is included in the Chain of Custody Kit (T282).
2. If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| COCH | Chain of Custody Processing | No | Yes |
| ADLTX | Adulterants Survey, CoC, U | Yes | Yes |
Testing Algorithm
Adulterants testing will be performed on all chain of custody urine samples as per regulatory requirements.