Test Code PGKC Phosphoglycerate Kinase Enzyme Activity, Blood
Reporting Name
Phosphoglycerate Kinase, BPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia, especially if X-linked inheritance pattern.
Evaluation of individuals with myopathic or neurologic symptoms
Method Name
Only available as part of a profile. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-EEEV1 / Red Blood Cell (RBC) Enzyme Evaluation, Blood
Kinetic Spectrophotometry (KS)
Specimen Required
Only available as part of a profile. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation, Blood
-EEEV1 / Red Blood Cell (RBC) Enzyme Evaluation, Blood
Specimen Type
Whole Blood ACD-BSpecimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood ACD-B | Refrigerated | 20 days |
Reject Due To
Gross hemolysis | Reject |
Reference Values
Only available as part of a profile. For more information see:
-HAEV1 / Hemolytic Anemia Evaluation
-EEEV1 / Red Blood Cell (RBC) Enzyme Evaluation
≥12 months: 142-232 U/g Hb
Reference values have not been established for patients who are younger than 12 months.
Interpretation
In phosphoglycerate kinase deficiency, red blood cell activity levels have been reported ranging from 1% to 49% of mean normal; however, affected patients more typically have values less than 20% of normal mean.(1)
Day(s) Performed
Weekly
Report Available
5 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82657
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
PGKC | Phosphoglycerate Kinase, B | 44053-7 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
PGKCL | Phosphoglycerate Kinase, B | 44053-7 |