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HelpTest Code PGN Pregabalin, Serum
Reporting Name
Pregabalin, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Monitoring serum pregabalin (Lyrica) concentrations, assessing compliance, and adjusting dosage in patients
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect specimen immediately before next scheduled dose.
2. Within 2 hours of collection, centrifuge, and aliquot serum into a plastic vial.
Specimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
2.0-5.0 mcg/mL
Interpretation
The serum concentration should be interpreted in the context of the patient's clinical response and other clinical tests. This may provide useful information for patients showing poor response, noncompliance, or adverse effects. Toxicity can occur with concentrations greater than or equal to 10 mcg/mL.
Day(s) Performed
Monday
Report Available
2 to 7 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PGN | Pregabalin, S | 47414-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 65119 | Pregabalin, S | 47414-8 |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.