Test Code PLFAT Cryptococcus Antigen Titer, Lateral Flow Assay, Pleural Fluid
Reporting Name
Cryptococcus Ag Titer, LFA, PFPerforming Laboratory
Mayo Clinic Laboratories in RochesterUseful For
Diagnosis of infection with Cryptococcus species
Method Name
Only orderable as a reflex. For more information see PLFA / Cryptococcus Antigen Screen, Lateral Flow Assay, Pleural Fluid.
Lateral Flow Assay (LFA)
Specimen Required
Only orderable as a reflex. For more information see PLFA / Cryptococcus Antigen Screen, Lateral Flow Assay, Pleural Fluid.
Specimen Type
Pleural FluidSpecimen Minimum Volume
0.25 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Pleural Fluid | Refrigerated (preferred) | 21 days | |
Frozen | 30 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
Only orderable as a reflex. For more information see PLFA / Cryptococcus Antigen Screen, Lateral Flow Assay, Pleural Fluid.
Interpretation
The presence of cryptococcal antigen in pleural fluid is indicative of infection with Cryptococcus species.
Monitoring cryptococcal antigen levels as a means to determine response to therapy is discouraged, as antigen levels may persist despite adequate treatment and disease resolution.
A negative result indicates lack of infection; however rare cases of false-negative results have been reported. Fungal culture should always be ordered alongside antigen testing.
Day(s) Performed
Monday through Sunday
Report Available
2 daysTest Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87899
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
PLFAT | Cryptococcus Ag Titer, LFA, PF | 11473-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
48431 | Cryptococcus Ag Titer, LFA, PF | 11473-6 |
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.