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Test Code RA1U Alpha-1-Microglobulin, Random, Urine

Reporting Name

Alpha-1-Microglobulin, Random, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessment of renal tubular injury or dysfunction using random urine specimens

 

Screening for tubular abnormalities

 

Detecting chronic asymptomatic renal tubular dysfunction (2)

Method Name

AIMR: Immunonephelometry

CRETR: Enzymatic Colorimetric Assay


Specimen Required


Container/Tube: Plastic, 5-mL tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

ALPHA 1- MICROGLOBULIN/CREATININE RATIO:

≥18 years: <35 mg/g creatinine

Reference values have not been established for patients younger than 18 years of age.

 

CREATININE:

≥18 years old: 16-326 mg/dL

Reference values have not been established for patients younger than 18 years of age.

Interpretation

Alpha-1-microglobulin above the reference values may indicate a proximal tubular dysfunction. As suggested in the literature, 7 mg/g creatinine is an upper reference limit for pediatric patients aged 1 month to 15 years.(3)

Day(s) Performed

Monday, Wednesday and Friday

Report Available

1 to 4 days

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83883

82570

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RA1U Alpha-1-Microglobulin, Random, U 48415-4

 

Result ID Test Result Name Result LOINC Value
A1M_U Alpha-1-Microglobulin, Random, U 46723-3
CRETR Creatinine, Random, U 2161-8
A1M_R A1M/Creat Ratio 48415-4

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Profile Information

Test ID Reporting Name Available Separately Always Performed
AIMR Alpha-1-Microglobulin, Random, U No Yes
CRETR Creatinine, Random, U Yes, (Order RCTUR) Yes