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Test Code SMAT Smooth Muscle Antibody Titer, Serum

Reporting Name

Smooth Muscle Ab Titer, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes

Method Name

Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.

 

Indirect Immunofluorescence


Specimen Required


Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.

 

Supplies: Sarstedt Aliquot Tube, 5 mL (T914) 

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.8 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial


Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-Treated Reject

Reference Values

Only orderable as part of a reflex. For more information see SMAS / Smooth Muscle Antibody Screen, Serum.

 

Negative

Reference values apply to all ages.

Interpretation

Positivity for smooth muscle antibodies (SMA) may help support a diagnosis of autoimmune hepatitis (AIH) following exclusion of other causes of hepatitis.

 

A negative result for SMA does not exclude a diagnosis of AIH.

Day(s) Performed

Monday through Saturday

Report Available

2 to 4 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86015

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SMAT Smooth Muscle Ab Titer, S 5358-7

 

Result ID Test Result Name Result LOINC Value
608956 Smooth Muscle Ab Titer, S 5358-7

Testing Algorithm

If the smooth muscle antibody (SMA) screen is equivocal or positive, then the SMA titer will be performed at an additional charge.