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Test Code STFR Soluble Transferrin Receptor (sTfR), Serum

Reporting Name

Soluble Transferrin Receptor (sTfR)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of suspected iron deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status, including:

-Cystic fibrosis patients who frequently have inflammation or infections(2-3)

-Evaluating insulin-dependent diabetics who may have iron-deficiency resulting from gastric autoimmunity and atrophic gastritis(4)

Method Name

Immunoturbidimetric Assay


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.


Specimen Type

Serum

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 90 days
  Refrigerated  7 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject

Reference Values

1.8-4.6 mg/L

It is reported that African Americans may have slightly higher values.

Interpretation

Soluble transferrin receptor (sTfR) concentrations are inversely related to iron status; sTfR elevates in response to iron deficiency and decreases in response to iron repletion.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84238

LOINC Code Information

Test ID Test Order Name Order LOINC Value
STFR Soluble Transferrin Receptor (sTfR) 30248-9

 

Result ID Test Result Name Result LOINC Value
STFR Soluble Transferrin Receptor (sTfR) 30248-9