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Test Code TGABI Thyroglobulin Antibody, Serum


Specimen Required


Only orderable as part of profile. For more information see IETG / Interference Evaluation Heterophile, Thyroglobulin Tumor Marker, Serum.

 

Patient Preparation: For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Initial testing as a part of evaluating suspected interference from heterophile antibodies causing a falsely elevated thyroglobulin result

Method Name

Only orderable as part of profile. For more information see IETG / Interference Evaluation Heterophile, Thyroglobulin Tumor Marker, Serum.

 

Immunoenzymatic Assay

Reporting Name

Thyroglobulin Antibody, S

Specimen Type

Serum Red

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject
 

Reference Values

Only orderable as part of profile. For more information see IETG / Interference Evaluation Heterophile, Thyroglobulin Tumor Marker, Serum.

 

<1.8 IU/mL

Reference values apply to all ages.

Interpretation

Anti-thyroglobulin (Tg) antibodies (Ab) may interfere with the measurement of Tg. TgAb should be measured in conjunction with every measurement of serum Tg to rule out potential interference. Anti-TgAb greater or equal to 1.8 IU/mL are likely to cause interference in the Tg immunoassay.

 

In the Beckman Access Tg immunoassay utilized in this interference evaluation, the presence of TgAb is most likely to cause a reduction in measured Tg concentrations. Measurement of Tg by mass spectrometry is not affected by the presence of TgAb.

Day(s) Performed

Monday through Saturday

Report Available

3 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86800

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TGABI Thyroglobulin Antibody, S 56536-6

 

Result ID Test Result Name Result LOINC Value
TGABI Thyroglobulin Antibody, S 56536-6