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Test Code THCM 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Meconium

Reporting Name

Carboxy-THC Confirmation, M

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)


Ordering Guidance


For chain-of-custody testing, order THCMX / 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Type

Meconium

Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Specimen Stability Information

Specimen Type Temperature Time
Meconium Frozen (preferred) 28 days
  Refrigerated  21 days
  Ambient  14 days

Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers		 Reject

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography tandem mass spectrometry result.

Cutoff concentration: 5 ng/g

Interpretation

The presence of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid at 5 ng/g or greater is indicative of in utero drug exposure up to 5 months before birth.

Day(s) Performed

Monday through Sunday

Report Available

2 to 3 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

G0480

80349 (if appropriate for select payers)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THCM Carboxy-THC Confirmation, M 69007-3

 

Result ID Test Result Name Result LOINC Value
31863 Carboxy-THC 69007-3
31876 Interpretation 69050-3
31877 Chain of Custody 77202-0

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.