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Test Code TULG Francisella tularensis Antibody, IgG, ELISA, Serum

Reporting Name

F. tularensis Ab, IgG ELISA, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluating the presence of IgG antibodies in patients with suspected tularemia caused by Francisella tularensis

 

This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years following resolution of disease.

Method Name

Only orderable as part of a profile. For more information see TULAB / Francisella tularensis Antibody, IgM and IgG, ELISA, Serum.

 

Enzyme-Linked Immunosorbent Assay (ELISA)


Specimen Required


Only orderable as part of a profile. For more information see TULAB / Francisella tularensis Antibody, IgM and IgG, ELISA, Serum.

 

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat-inactivated specimen Reject

Reference Values

Only orderable as part of a profile. For more information see TULAB / Francisella tularensis Antibody, IgM and IgG, ELISA, Serum.

 

Negative

Reference values apply to all ages.

Interpretation

IgM result

IgG result

Interpretation

Negative

Negative

No antibodies to Francisella tularensis detected. Antibody response may be negative in samples collected too soon following infection/exposure. Repeat testing on a new sample in 1 to 2 weeks if clinically indicated.

Positive

Negative

IgM class antibodies to F tularensis detected, suggesting current or recent infection. Repeat testing in 1 to 2 weeks to detect seroconversion of IgG may be considered to confirm the diagnosis.

Positive

Borderline

Borderline

Negative

Questionable presence of IgM antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks.

Borderline

Positive

IgG class antibodies to F tularensis detected suggesting recent or past infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required.

Borderline

Borderline

Questionable presence of IgM and IgG class antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks.

Positive

Positive

IgM and IgG class antibodies to F tularensis detected suggesting current, recent or past infection. Cross-reactions may occur in patients with a current or prior Brucella infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required.

Negative

Positive

IgG class antibodies to F tularensis detected suggesting recent or past infection. Clinical correlation alongside presentation, exposure history and other laboratory findings required.

Negative

Borderline

Questionable presence of IgG antibodies to F tularensis. Consider repeat testing in 1 to 2 weeks.

Day(s) Performed

Tuesday, Thursday

Report Available

Same day/1 day

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86668

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TULG F. tularensis Ab, IgG ELISA, S 93717-7

 

Result ID Test Result Name Result LOINC Value
TULG F. tularensis Ab, IgG ELISA, S 93717-7