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Test Code VEGF Vascular Endothelial Growth Factor, Plasma

Reporting Name

Vascular Endothelial Growth Fctr, P

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Evaluation of patients with suspected POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, particularly in differentiating from other forms of polyneuropathy and/or monoclonal plasma cell disorders

Method Name

Electrochemiluminescence Immunoassay (ECLIA)


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Lavender-top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. Centrifuge at 4° C, 1500 x g for 10 minutes.

3. Aliquot plasma into plastic vial.

4. Freeze specimen within 2 hours of collection.


Specimen Type

Plasma EDTA

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma EDTA Frozen (preferred) 21 days
  Refrigerated  24 hours

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus Reject
Heat-treated Reject

Reference Values

≤96.2 pg/mL

Interpretation

Elevated concentration of vascular endothelial growth factor (VEGF) may be consistent with a diagnosis of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome.

 

Decreasing concentrations of VEGF over time in a patient with POEMS syndrome may be consistent with a therapeutic response.

Day(s) Performed

Tuesday, Thursday

Report Available

2 to 7 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VEGF Vascular Endothelial Growth Fctr, P 34694-0

 

Result ID Test Result Name Result LOINC Value
63019 VEGF, P 34694-0