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Test Code VLTU Volatile Screen, Random, Urine

Reporting Name

Volatile Scrn, U

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detecting the presence of acetone, methanol, isopropanol, or ethanol in urine with subsequent quantitation

Method Name

Headspace Gas Chromatography with Flame Ionization Detector (HSGC-FID)


Ordering Guidance


For best clinical correlation, the recommended tests are either VLTS / Volatile Screen, Serum; or VLTB / Volatile Screen, Blood.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative is required.


Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Methanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

 

Ethanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

 

Isopropanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

 

Acetone:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

Interpretation

Methanol:

The presence of methanol indicates exposure that may result in intoxication, central nervous system (CNS) depression, and metabolic acidosis. Ingestion of methanol can be fatal if patients do not receive immediate medical treatment.

 

Ethanol:

The presence of ethanol indicates exposure that may result in intoxication, CNS depression, and metabolic acidosis.

 

Isopropanol:

The presence of isopropanol indicates exposure that may result in intoxication and CNS depression. Ingestion of isopropanol can be fatal if patients do not receive immediate medical treatment.

 

Acetone:

The presence of acetone may indicate exposure to acetone; it is also a metabolite of isopropanol and may be detected during ketoacidosis.

Day(s) Performed

Monday through Saturday

Report Available

1 to 2 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80320

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VLTU Volatile Scrn, U 24350-1

 

Result ID Test Result Name Result LOINC Value
8826 Volatile Scrn, U 12983-3
30904 Methanol, U 5695-2
30905 Ethanol, U 5645-7
30906 Acetone, U 5570-7
30907 Isopropanol, U 9434-2
34378 Chain of Custody 77202-0

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.

Testing Algorithm

This test includes analysis of methanol, ethanol, isopropanol, and acetone.