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Test Code VWFMP von Willebrand Factor Multimer Analysis, Plasma

Reporting Name

von Willebrand Factor Multimer, P

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

As a reflex component of several coagulation consultation unit codes, when indicated

 

When results of complementary laboratory tests are abnormally low or discordant (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von Willebrand Factor Activity, Plasma; and VWAG / von Willebrand Factor Antigen, Plasma)

 

To subtype von Willebrand disease (VWD) (primarily identify variants of type 2 VWD)

 

As an aid in determining appropriate treatment

Method Name

Only orderable as part of a coagulation reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

ACBL / Bleeding Diathesis Profile, Comprehensive, Plasma

AVWPR / von Willebrand Disease Profile, Plasma

 

Agarose Gel Electrophoresis


Specimen Required


Only orderable as part of a coagulation reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

AVWPR / von Willebrand Disease Profile, Plasma

 

For more information see Coagulation Guidelines for Specimen Handling and Processing.


Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 42 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

Only orderable as part of a coagulation reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

AVWPR / von Willebrand Disease Profile, Plasma

 

An interpretive report will be provided.

Interpretation

The plasma von Willebrand factor (VWF) multimer analysis is a qualitative visual assessment of the size spectrum and the banding pattern of vWF multimers.

 

This test is used to identify variants of type 2 von Willebrand disease (VWD) that have fewer of the largest multimers, have unusually large multimers, or have qualitatively abnormal "bands" that indicate an abnormal vWF structure.

Day(s) Performed

Monday, Tuesday

Report Available

7 to 14 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

85247

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VWFMP von Willebrand Factor Multimer, P 32217-2

 

Result ID Test Result Name Result LOINC Value
604411 von Willebrand Factor Multimer, P 32217-2
604412 VWF Multimer Interpretation 48595-3