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Test Code WNVCI West Nile CSF Interpretation

Reporting Name

West Nile CSF Interpretation

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Interpretation of testing for a laboratory diagnosis of infection with West Nile virus using spinal fluid specimens

 

Aids in diagnosis of central nervous system infection with West Nile virus

Method Name

Only orderable as part of a profile. For more information see WNC / West Nile Virus Antibody, IgG and IgM, Spinal Fluid.

 

Technical Interpretation


Specimen Required


 


Specimen Type

CSF

Specimen Stability Information

Specimen Type Temperature Time Special Container
CSF Refrigerated (preferred) 7 days
  Frozen  30 days

Reference Values

Only orderable as part of a profile. See WNC / West Nile Virus Antibody, IgG and IgM, Spinal Fluid.

 

An interpretive report will be provided.

Interpretation

IgM:

A positive result is consistent with the acute phase of West Nile virus (WNV) meningitis or encephalitis. In the very early stages of acute WNV infection, IgM may be detectable in spinal fluid (CSF) before it becomes detectable in serum.

 

A negative result may indicate absence of disease. However, specimens collected too early in the acute phase may be negative for IgM-class antibodies to WNV. If WNV central nervous system infection is suspected, a second specimen should be collected in 1 to 2 weeks and tested.

 

IgG:

A positive result may indicate recent or past central nervous system (CNS) infection with WNV. Clinical correlation is necessary.

 

This assay is unable to distinguish between intrathecal antibody synthesis and serum antibodies introduced into the CSF at the time of lumbar puncture or from a breakdown in the blood-brain barrier. Positive results should be interpreted with other laboratory and clinical data prior to a diagnosis of CNS infection.

Day(s) Performed

Monday, Wednesday, Friday

Report Available

Same day/1 day

Test Classification

Not Applicable

LOINC Code Information

Test ID Test Order Name Order LOINC Value
WNVCI West Nile CSF Interpretation 69048-7

 

Result ID Test Result Name Result LOINC Value
WNVCI West Nile CSF Interpretation 69048-7