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HelpTest Code YMCRO Y Chromosome Microdeletions, Molecular Detection, Varies
Reporting Name
Y MicrodeletionPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Evaluating men with azoospermia, severe oligozoospermia, or otherwise unexplained male factor infertility
Method Name
Polymerase Chain Reaction (PCR)
Specimen Required
Patient Preparation: A previous bone marrow transplant from an allogeneic donor will interfere with testing. For instructions for testing patients who have received a bone marrow transplant, call 800-533-1710.
Specimen Type: Whole blood
Container/Tube:
Preferred: Lavender top (EDTA) or yellow top (ACD)
Acceptable: None
Specimen Volume: 3 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Additional Information:
1. Specimens are preferred to be received within 4 days of collection. Extraction will be attempted for specimens received after 4 days, and DNA yield will be evaluated to determine if testing may proceed.
2. To ensure minimum volume and concentration of DNA is met, the preferred volume of blood must be submitted. Testing may be canceled if DNA requirements are inadequate.
Specimen Type
VariesSpecimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Ambient (preferred) | |
| Frozen | ||
| Refrigerated | ||
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
An interpretive report will be provided.
Interpretation
The interpretive report includes an overview of the findings as well as the associated clinical significance.
Day(s) Performed
Wednesday
Report Available
7 to 10 daysTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
81403-DAZ/SRY (deleted in azoospermia and sex determining region Y) (eg, male infertility), common deletions (eg, AZFa, AZFb, AZFc, AZFd)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| YMCRO | Y Microdeletion | 35456-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 53364 | Result Summary | 50397-9 |
| 53365 | Result | 82939-0 |
| 53366 | Interpretation | 69047-9 |
| 53367 | Specimen | 31208-2 |
| 53368 | Source | 31208-2 |
| 53369 | Released By | 18771-6 |
Forms
1. New York Clients-Informed consent is required. Document on the request form or electronic order that a copy is on file
-Informed Consent for Genetic Testing (T576)
-Informed Consent for Genetic Testing-Spanish (T826)
2. Molecular Genetics: Congenital Inherited Diseases Patient Information (T521)